Synthesis and biological activity of new silver complexes with N-heterocyclic carbene ligands

Silver complexes of N-heterocyclic carbene (NHC) have been synthesized, structured, and tested for antibacterial activity. All the silver–NHC (10–13) were made by reacting benzimidazolium salts with Ag2O at room temperature in dichloromethane as a solvent. The hypothesized structures are supported 1H NMR, 13 C IR analysis novel compounds. In vitro efficacy against Gram-positive S. aureus Gram-negative Bacteria E. coli was on number Ag–NHC complexes.